The importance of biological databases in biological discovery. Biological databases play a central role in bioinformatics. A DNA database is a stored set of genetic profiles that can be used for a variety of needs. They offer scientists the opportunity to access a wide variety of biologically relevant data, including the genomic sequences of an increasingly broad range of organisms. A biological database is a collection of data that is organized so that its contents can easily be accessed, managed, and updated. A protein database is one or more datasets about proteins, which could include a protein’s amino acid sequence, conformation, structure, and … Originally they were just sequence collections, but they have grown to store different biological databases heavily interconnected and they provide powerful interfaces to search and browse the stored information. EMBnet MCB, feb 2005 Distribution of databases Nucleic Acids Research Database Issue. are no longer published in a conventional manner, but directly submitted to databases. Protocol Online protocol-online.org. Biological databases play a central role in bioinformatics. • Essential tools for biological research. • Exponential growth in biological data. The distinction between the concepts of biological relevance and statistical significance should be Bioinformatics has its importance in the management and collection of biological data. Bioinformatics is an integrated interdisciplinary field it includes various subjects such as math, chemistry, genomics, proteomics, etc. An important resource for finding biological databases is a special yearly issue of the journal Nucleic Acids Research (NAR). assessment of the evidence provided by these studies. INTRODUCTION TO BIOLOGICAL DATABASES SARFARAZ HUSSAIN Department of Bioinformatics & Biotechnology GCU- Faisalabad NOTE: Most slides derived from NCBI’s field guide / sarfraz1412@gmail.com 2. Confusion in the use of words such as “significance”, “relevance” and “importance” can therefore hinder the assessment. Its mission is to make life science research more efficient and reproducible by curating and hosting high-quality, experimentally validated, freely accessible protocols. Statistical analysis of the data is central to this assessment. Law enforcement agencies use these databases to track collected evidence. These databases may be public or private. Why biological databases ? Biological databases offer access to a wide variety of biological data and play a central role in bioinformatics56 7. They offer scientists the opportunity to access sequence and structure data for tens of thousands of sequences from a broad range of organisms. 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